Exploring the Connection Between NAD+ and Fertility
Emerging research highlights the crucial role of nicotinamide adenine dinucleotide (NAD+) in reproductive health. A study published in Frontiers in Endocrinology found that low NAD+ levels are associated with a decline in spermatogenesis in both transgenic and aging mice, suggesting that NAD+ depletion may impair sperm production and quality.
As we age, NAD+ levels naturally decline, leading to increased oxidative stress and DNA damage in reproductive cells. This decline can negatively impact egg and sperm quality, contributing to reduced fertility. By replenishing NAD+ levels, it’s possible to enhance mitochondrial function, reduce oxidative stress, and improve overall reproductive outcomes.
Understanding NAD+ and Its Role in Reproductive Health
NAD+ is a coenzyme found in all living cells, essential for various metabolic processes, including energy production and DNA repair. In the context of fertility, NAD+ supports the health and function of oocytes (egg cells) and spermatozoa (sperm cells).
Impact on Female Fertility
In women, aging is associated with a decline in both the quantity and quality of oocytes. This decline is partly due to increased oxidative stress and reduced mitochondrial function within the ovaries. Research indicates that decreased NAD⁺ levels contribute to these age-related changes, leading to impaired egg quality and reduced fertility.
Impact on Male Fertility
Similarly, in men, NAD⁺ levels decrease with age, affecting sperm quality. Lower NAD⁺ levels are linked to reduced sperm motility, increased DNA fragmentation, and overall diminished fertility. Enhancing NAD⁺ levels may help mitigate these effects, supporting healthier sperm and improved reproductive outcomes.
Supporting NAD+ Levels for Fertility
Maintaining optimal NAD⁺ levels is crucial for reproductive health. While the body naturally produces NAD⁺, levels decline with age and certain lifestyle factors. Supplementation with NAD⁺ precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), has been shown to effectively increase NAD⁺ levels in the body.
How Joi + Blokes Can Support Your Fertility Journey
At Joi + Blokes, we understand the importance of cellular health in reproductive function. We offer NAD+ Nasal Spray and injectable solutions designed to boost your body’s NAD+ levels effectively. Our services aim to support your fertility journey by enhancing cellular energy production, promoting DNA repair, and improving overall reproductive health.
Meet Lindsey VanSchoyck
Lindsey is a board-certified family nurse practitioner with 16+ years of experience. She specializes in hormone optimization, peptide therapy, and lifestyle medicine, taking a holistic approach to care. Lindsey holds a BA in Psychology from Butler University, a BSN from Eastern Illinois University, and an MSN from Chamberlain University. She’s currently pursuing her doctorate in lifestyle medicine at Florida State University. Lindsey is a National Board Certified Health Coach, a CrossFit Level 2 coach and gym owner, and holds multiple nutrition, precision medicine, and exercise certifications. She completed a fellowship in genomics and precision medicine from Wild Health. Lindsey uses her expertise to develop individualized care plans, empowering patients to take charge of their health through compassion and science.
