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As a woman in my forties, what hormones do I need?

How HRT and NAD+ Infusions Can Fight Brain Fog, Fatigue, and Help You Feel LIke Yourself Again

Your forties can be empowering, liberating – and confusing – all at the same time. One minute you’re thriving, the next you’re wondering why your energy has plummeted, your sleep has gone haywire, and your focus seems to have packed up and left. The key culprit? Hormonal changes. 

As you enter perimenopause – the years leading up to menopause – your hormone levels begin to fluctuate. This shift can trigger a range of physical and emotional symptoms that leave many women feeling off-balance and overwhelmed. But there are effective ways to regain control, from hormone replacement therapy (HRT) to the new on-trend NAD+ infusions that support health and mental clarity. 

At Joi + Blokes, we specialise in personalized, science-backed wellness plans designed to help you thrive – not just survive – through hormonal transitions. 

Which Hormones Do You Actually Need in Your Forties?

Let’s break down the key players:

Estrogen 

This hormone regulates your menstrual cycle and supports brain, bone, and skin health. As estrogen declines, you may experience hot flashes, night sweats, anxiety, memory lapses and vaginal dryness.

Progesterone

Known for its calming effect, progesterone helps regulate mood and sleep. When it drops, you may notice irregular periods, irritability, insomnia and heavier bleeding. 

Testosterone 

Often overlooked in women, testosterone contributes to muscle tone, mental clarity, sex drive and motivation. Low levels are linked to fatigue, low libido and difficulty concentrating. 

Why Hormone Replacement Therapy (HRT) Might Be Right For You 

If you’ve been feeling ‘off’ and can’t quite explain why, HRT could be the missing piece. At Joi + Blokes, we offer bioidentical hormone therapy that mimics the hormones your body naturally produces – offering a gentler, more tailored approach to treatment. 

Benefits of HRT include: 

  • More stable moods and reduced anxiety 
  • Improved sleep quality 
  • Enhanced energy and mental clarity 
  • Boosted libido and confidence
  • Protection against osteoporosis and heart disease

A survey conducted by Joi + Blokes found that HRT has changed women’s lives and after 6 months:

  • 53% saw increased energy levels
  • 37% experienced better sleep 
  • 29% reported higher libido

“I am a new person,” explains Christine, a Joi + Blokes customer who thought she could “power through” menopause. But now, with hormone therapy, she’s found that her “funk” is gone, and her energy is higher than ever at 56.

Find out about our HRT programs designed specifically for women in perimenopause and beyond. 

The Power of NAD+ Infusions: Your Secret Weapon for Energy and Focus

Even with hormones in check, many women in their forties still struggle with energy crashes, brain fog and burnout. That’s where NAD+ therapy comes in. 

What is NAD+? 

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme that plays a key role in energy production, metabolism, and cellular repair.

  • Involved in energy production
  • Cofactor for DNA repair and cellular health
  • Aids in immune system balance and liver function
  • Supports cognitive health
  • Protects against oxidative stress
  • May slow down the aging process

As we age, NAD+ levels naturally decline – especially during times of hormonal transition. This can leave you feeling sluggish, foggy and less resilient. 

Why Try NAD+?

Women who undergo NAD+ therapy often report:

  • Sharper mental focus 
  • Increased physical energy 
  • Better mood and sleep 
  • Enhanced skin tone and cellular renewal 

Ready to feel focused and energised again? Explore our NAD+ therapy and see how it can support your midlife wellness journey. 

Support for the Whole You 

Your forties don’t have to feel like a slow decline. In fact, with the right support, this can be your most powerful and energized decade yet. Whether you’re struggling with sleep, mood swings, fatigue, low libido or all of the above, there are science-backed solutions available. 

At Joi + Blokes, we offer a full spectrum of services – including lab testing, HRT, NAD+, and 1-on-1 clinician meetings – to help you understand your hormones and take back control of your health. 

Take the First Step Today 

If you’re ready to feel like yourself again, we’re here to help: 

Because your energy, clarity and confidence aren’t behind you – they’re waiting to be unlocked.


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