Clomiphene

Clomiphene stimulates the body’s natural testosterone production by acting on the hypothalamic-pituitary-gonadal (HPG) axis. It functions as a selective estrogen receptor modulator (SERM), blocking estrogen receptors in the hypothalamus. This prevents estrogen from signaling the brain to reduce testosterone production.

By blocking estrogen’s negative feedback, clomiphene triggers the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus, which then stimulates the pituitary gland to increase luteinizing hormone (LH) and follicle-stimulating hormone (FSH) production.

• LH signals the testes to produce more testosterone
• FSH supports sperm production, maintaining fertility

Unlike traditional testosterone replacement therapy (TRT), which can suppress natural testosterone and sperm production, clomiphene keeps the body’s hormonal regulation intact while boosting testosterone levels. This makes it a preferred option for men looking to optimize testosterone while preserving fertility.

Most individuals begin noticing improvements in energy, mood, and libido within a few weeks. Full benefits, including muscle strength and metabolism changes, typically develop over 6 weeks.

Most people tolerate clomiphene well, but some may experience mild side effects like headaches, mood changes, or temporary vision disturbances. Your provider will monitor your response and adjust your treatment if needed.

Clomiphene and enclomiphene are taken orally, making treatment simple and convenient. These medications work by stimulating your body’s natural testosterone production, leading to benefits such as:

• Increased sex drive
• Stronger erections
• Improved mood
• Higher energy levels
• Enhanced metabolism

For personalized guidance, consult with a healthcare provider to determine if clomiphene or enclomiphene is right for you

Clomiphene can help address a range of symptoms associated with low testosterone, including:

• Low sex drive
• Brain fog
• Mood changes & fatigue
• Erectile performance issues
• Lower sperm count
• Hair loss
• Unwanted belly fat

At Joi+ Blokes, we take a holistic, preventative approach to care, which means many advanced treatments and lab tests are not typically covered by insurance. However, we do offer insurance-pay options for certain prescriptions:

• Women’s health medications like estrogen and progesterone can be sent to your local pharmacy, where you may use your insurance benefits.
  
• Thyroid medications will be sent to your local pharmacy, allowing you to utilize your insurance coverage.
  
• FDA-approved GLP-1/GIP medications for weight loss and type 2 diabetes, including Ozempic, Wegovy, Zepbound, and Mounjaro, may also be eligible for coverage.
  

While we assist with prior authorizations and prescription submissions, we do not bill insurance directly. We recommend checking with your insurance provider for specific coverage details.

Yes! You can use your HSA or FSA funds to cover eligible purchases. We are happy to provide a detailed receipt and a Letter of Medical Necessity (LMN) from your provider. You can then submit these documents to your HSA/FSA account for potential reimbursement. Since coverage varies by plan, we recommend checking with your provider to confirm eligibility.

Email us at info@joiandblokes.com with any more questions.