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Longevity
Lab + clinician visit required

Low Dose Naltrexone (LDN)

LDN is a modulator of immune function that may help balance the body's inflammatory response and support cellular repair. LDN has been explored for its potential to reduce chronic inflammation, enhance immune resilience, and support thyroid health.

Subscription $63/mo, billed quarterly. Initial lab required for prescription. Lab billed separately.

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Important Safety Information

All prescriptions require a consultation with a licensed provider, either asynchronously or synchronously.  If the provider determines the medication isn't appropriate for you, you'll receive a full refund. Our drugs may include compounded products that have not been approved by the FDA. The FDA does not verify the safety or effectiveness of compounded drugs including compounded Liraglutide For Weight loss. Our specialists may prescribe this medication off label from its intended use.... Read more

Balances Immune Response

Regulates inflammation and immune function, promoting a more balanced and resilient system.

Enhances Natural Endorphins

LDN may help increase endorphin levels, supporting mood and overall vitality.

Support for Daily Comfort & Energy

May help with physical discomfort and fatigue, promoting overall well-being and day-to-day function.

Inflammation’s worst nightmare

Feeling off? LDN steps to help support immune balance, cellular function, and keep things running smoothly.

  • May help modulate inflammation
  • Aids in immune system regulation
  • Assists in pain management
  • Promotes emotional balance and focus
  • Being studied in relation to autoimmune support
  • Supports thyroid and hormone health
  • Contributes to cellular health and recovery

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What’s included?

Board-Certified Clinicians

Board-Certified Clinicians

Expert guidance and personalized care.

 

1:1 Coaching

1:1 Coaching

Personalized support to help you achieve your health goals.

 

Lifestyle & Nutrition Support

Lifestyle & Nutrition Support

Holistic recommendations for diet, exercise, and lifestyle modifications.

 

Convenience of Care

Convenience of Care

Hassle-free treatment with medications delivered straight to your door.

 

Unlimited Messaging

Unlimited Messaging

Direct access to your care team whenever you need it.

 

Community

Community

Support from others on the same journey—feeling better, together.

 

Have questions? We're here to help

LDN has been explored for its potential in supporting autoimmune conditions, chronic pain, and inflammatory disorders. It is commonly used in conditions such as fibromyalgia, multiple sclerosis (MS), rheumatoid arthritis, Hashimoto’s thyroiditis, Crohn’s disease, ulcerative colitis, and chronic fatigue syndrome. Research also suggests potential benefits for neurological conditions, mood disorders, and immune system regulation.


LDN is generally well-tolerated, but it’s important to check for potential interactions. Certain medications, especially opioids and immunosuppressants, may interfere with its effects. Always consult with your healthcare provider before combining LDN with other medications to ensure safety and effectiveness.


Naltrexone is FDA-approved in higher doses for treating opioid and alcohol dependence. However, Low Dose Naltrexone (LDN) is not officially FDA-approved for conditions like autoimmune disorders, chronic pain, or inflammation but is commonly prescribed off-label based on emerging research and clinical use.


LDN is generally well-tolerated, but some individuals may experience temporary side effects as their body adjusts. These can include vivid dreams, difficulty sleeping, headaches, nausea, dizziness, or mild gastrointestinal discomfort. Most side effects are mild and resolve over time. If symptoms persist or worsen, consult your healthcare provider


At Joi+ Blokes, we take a holistic, preventative approach to care, which means many advanced treatments and lab tests are not typically covered by insurance. However, we do offer insurance-pay options for certain prescriptions:

 

  • Women’s health medications like estrogen and progesterone can be sent to your local pharmacy, where you may use your insurance benefits.
  • Thyroid medications will be sent to your local pharmacy, allowing you to utilize your insurance coverage.
  • FDA-approved GLP-1/GIP medications for weight loss and type 2 diabetes, including Ozempic, Wegovy, Zepbound, and Mounjaro, may also be eligible for coverage.

 

While we assist with prior authorizations and prescription submissions, we do not bill insurance directly. We recommend checking with your insurance provider for specific coverage details.


Yes! You can use your HSA or FSA funds to cover eligible purchases. We are happy to provide a detailed receipt and a Letter of Medical Necessity (LMN) from your provider. You can then submit these documents to your HSA/FSA account for potential reimbursement. Since coverage varies by plan, we recommend checking with your provider to confirm eligibility.


Email us at info@joiandblokes.com with any more questions.


Not sure where to start?

We recommend getting lab-tested first to give you access to a health coach and clinician that will help guide your personal health.

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Feel better, live longer

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